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Sulfides / Thiols


Sulfides or thioethers are a class of organic compounds that contain C-S-C linkage while thiols are sulfur analogues of alcohols. Many thiols have strong odours resembling that of garlic or rotten eggs. Sulfides are typically prepared by alkylation of thiols. Alternatively, they can be synthesized by the addition of a thiol to an alkene (thiol-ene reaction). Sulfides can be easily oxidized to sulfoxides, which can themselves be further oxidized to sulfones. They are readily alkylated to give stable sulfonium salts. Sulfides bind to metals to form thioether complexes or they can undergo reductive dealkylation in the presence of certain metals. Thiols can be prepared from alkyl halides via an S-alkylation of thiourea or sodium hydrosulfide. Thiolates are more potent nucleophiles than the corresponding alkoxides. As the functional group of the cysteine, it plays a very important role in biology, many cofactors feature thiols. Many commercial drugs also contain thiol group.

Product nameStructureCAS#G-code
2-Amino-5-(ethylthio)-1,3,4-thiadiazoleStructure of 2-Amino-5-(ethylthio)-1,3,4-thiadiazole[25660-70-2]GEO-00136
6-Amino-2-mercaptobenzothiazoleStructure of 6-Amino-2-mercaptobenzothiazole[7442-07-1]GEO-00151
4-Amino-2-mercaptopyrimidineStructure of 4-Amino-2-mercaptopyrimidine[333-49-3]GEO-00152
2-Amino-5-(methylthio)-1,3,4-thiadiazoleStructure of 2-Amino-5-(methylthio)-1,3,4-thiadiazole[5319-77-7]GEO-00174
New6-Anilino-1,3,5-triazin-2,4-dithiol monosodium saltStructure of 6-Anilino-1,3,5-triazin-2,4-dithiol monosodium salt[57343-38-1]GEO-04839
New1,3-BenzenedithiolStructure of 1,3-Benzenedithiol[626-04-0]GEO-03897
Benzene-1,4-dithiolStructure of Benzene-1,4-dithiol[624-39-5]GEO-04155
1,2-BenzenedithiolStructure of 1,2-Benzenedithiol[17534-15-5]GEO-00251
4-Benzylthio-1H-pyrazoleStructure of 4-Benzylthio-1H-pyrazole[308121-87-1]GEO-04063
5-Bromo-1,3-benzenedithiolStructure of 5-Bromo-1,3-benzenedithiol[1219501-75-3]GEO-04125
2-Bromo-4-fluoro-1-(methylthio)benzeneStructure of 2-Bromo-4-fluoro-1-(methylthio)benzene[91524-70-8]GEO-04054
(4-Bromophenyl)diphenylsulfonium triflateStructure of (4-Bromophenyl)diphenylsulfonium triflate[255056-44-1]GEO-04499
2-(tert-Butyl)benzenethiolStructure of 2-(tert-Butyl)benzenethiol[19728-41-7]GEO-04077
5-tert-Butyl-2-hydroxy-3-(methylthio)benzaldehydeStructure of 5-tert-Butyl-2-hydroxy-3-(methylthio)benzaldehyde[81322-70-5]GEO-02513
2-Chloroethyl ethyl sulfideStructure of 2-Chloroethyl ethyl sulfide[693-07-2]GEO-03411
5-Chloro-3-methylmercapto-1,2,4-thiadiazoleStructure of 5-Chloro-3-methylmercapto-1,2,4-thiadiazole[21735-15-9]GEO-02726
2-Chloro-6-methylthiophenol[18858-05-4]GEO-00733
(3-Chlorophenyl)methanethiol[25697-57-8]GEO-00766
Cyanomethyl-2,3,4,6-tetra-O-acetyl-a-D-thiomannopyranoside[61145-39-9]GEO-04234
Cyclohexene sulfide[286-28-2]GEO-00868
4-Cyclopentylamino-2-methanethiopyrimidine-5-carboxylic acid ethyl ester[211245-62-4]GEO-04295
4,6-Diamino-2-mercaptopyrimidine[1004-39-3]GEO-00921
3,5-Dichlorobenzenemethanethiol[65963-17-9]GEO-03033
Diethyl 2,6-dimethyl-4-(5-((5-methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)-1,4-dihydropyridine-3,5-dicarboxylateN/AGEO-03540
(3,4-Difluorophenyl)methanethiol[666752-97-2]GEO-01068
(2,5-Difluorophenyl)methanethiolN/AGEO-01067
(2,4-Difluorophenyl)methanethiol[170924-51-3]GEO-01066
5,6-Dihydro-1,4-dithiin-2,3-dicarboximideStructure of 5,6-Dihydro-1,4-dithiin-2,3-dicarboximide[24519-85-5]GEO-01089
2,3-Dihydro-1,4-dithiino[2,3-c]furan-5,7-dione[10489-75-5]GEO-01087
4,6-Dihydro-1H,3H-thieno[3,4-c]furan-1,3-dione[75532-25-1]GEO-04022
2,5-Dihydrothiophene-3,4-dicarboxylic acid[20688-07-7]GEO-04023
New3,4-DimercaptotolueneStructure of 3,4-Dimercaptotoluene[496-74-2]GEO-03465
1-(Dimethylamino)-2-propanethiol[1920-46-3]GEO-03732
2-(Dimethylamino)-1-propanethiol[66338-45-2]GEO-03243
3-(Dimethylamino)-1-propanethiol hydrochlorideStructure of 3-(Dimethylamino)-1-propanethiol hydrochloride[38048-81-6]GEO-03245
2-(Dimethylamino)-1-propanethiol hydrochloride[101724-24-7]GEO-03244
Dimethyl 2,5-dihydrothiophene-3,4-dicarboxylate[20946-32-1]GEO-04024
Dimethyl 2,6-dimethyl-4-(5-((5-methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)-1,4-dihydropyridine-3,5-dicarboxylateN/AGEO-03522
Dimethyl 2,6-dimethyl-4-(5-(pyridin-2-ylthio)furan-2-yl)-1,4-dihydropyridine-3,5-dicarboxylateN/AGEO-03494
2-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-ethanethiolStructure of 2-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-ethanethiol[76855-57-7]GEO-04479
4,5-Diphenyl-2-imidazolethiol[2349-58-8]GEO-01241
Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylateStructure of Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate[5909-24-0]GEO-01330
Ethyl 2,7,7-trimethyl-4-(5-((5-methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylateN/AGEO-03545
(2-Fluorophenyl)methanethiol[72364-46-6]GEO-01428
(4-Fluorophenyl)methanethiol[15894-04-9]GEO-01430
(3-Fluorophenyl)methanethiol[40096-23-9]GEO-01429
6-Hydroxy-2-mercaptopurineStructure of 6-Hydroxy-2-mercaptopurine[2487-40-3]GEO-01523
(Z)-2-Isocyano-3-(5-(pyridin-2-ylthio)furan-2-yl)acrylonitrileN/AGEO-03486
2-Mercapto-6-nitrobenzothiazoleStructure of 2-Mercapto-6-nitrobenzothiazole[4845-58-3]GEO-01654
(E)-Methyl 2-cyano-3-(5-((5-methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)acrylateN/AGEO-03525
(Z)-Methyl 2-cyano-3-(5-(pyridin-2-ylthio)furan-2-yl)acrylateN/AGEO-03485
(R)-2-Methylcysteine hydrochlorideStructure of (R)-2-Methylcysteine hydrochloride[148766-37-4]GEO-02622
3,4-(Methylenedioxy)thiophenolStructure of 3,4-(Methylenedioxy)thiophenol[5274-08-8]GEO-03999
6-Methyl-2-methylsulfanyl-1H-pyrimidin-4-oneStructure of 6-Methyl-2-methylsulfanyl-1H-pyrimidin-4-one[6328-58-1]GEO-02802
5-((5-Methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-carbaldehydeN/AGEO-03520
(E)-3-(5-((5-Methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)acrylic acidN/AGEO-03526
2-((5-((5-Methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)methylene)malononitrileN/AGEO-03523
4′-(Methylthio)acetophenoneStructure of 4'-(Methylthio)acetophenone[1778-09-2]GEO-01947
2-Methylthio-4-aminouracilStructure of 2-Methylthio-4-aminouracil[1195219-77-2]GEO-03079
2-Methylthio-2-imidazoline hydriodideStructure of 2-Methylthio-2-imidazoline hydriodide[5464-11-9]GEO-01949
4-(Methylthio)phenylacetic acidStructure of 4-(Methylthio)phenylacetic acid[16188-55-9]GEO-01963
3-(Methylthio)phenyl isocyanateStructure of 3-(Methylthio)phenyl isocyanate[28479-19-8]GEO-01964
4-(Methylthio)phenyl isocyanateStructure of 4-(Methylthio)phenyl isocyanate[1632-84-4]GEO-01965
New4-(Methylthio)phenyl isothiocyanateStructure of 4-(Methylthio)phenyl isothiocyanate[15863-41-9]GEO-01967
3-(Methylthio)phenyl isothiocyanateStructure of 3-(Methylthio)phenyl isothiocyanate[51333-80-3]GEO-01966
3-(Methylthio)propanoic acidStructure of 3-(Methylthio)propanoic acid[646-01-5]GEO-01970
6-(Methylthio)pyrimido[5,4-d]pyrimidin-4(1H)-oneStructure of 6-(Methylthio)pyrimido[5,4-d]pyrimidin-4(1H)-one[98550-19-7]GEO-04340
New5-Methylthio-1,3,4-thiadiazole-2-thiolStructure of 5-Methylthio-1,3,4-thiadiazole-2-thiol[6264-40-0]GEO-01973
PhenylthiotrimethylsilaneStructure of Phenylthiotrimethylsilane[4551-15-9]GEO-02142
5-(Pyridin-2-ylthio)furan-2-carbaldehyde[709635-68-7]GEO-03484
(2-Pyrimidylthio)acetic acidStructure of (2-Pyrimidylthio)acetic acid[88768-45-0]GEO-02198
3,3,6,6-Tetramethyl-9-(5-((5-methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dioneN/AGEO-03528
4-(Trifluoromethoxy)phenylmethanethiolStructure of 4-(Trifluoromethoxy)phenylmethanethiol[175278-03-2]GEO-02375
3-(Trifluoromethyl)phenylmethanethiolStructure of 3-(Trifluoromethyl)phenylmethanethiol[25697-55-6]GEO-02383
2-(Trifluoromethyl)phenylmethanethiolStructure of 2-(Trifluoromethyl)phenylmethanethiol[26039-98-5]GEO-02382
4-(Trifluoromethyl)phenylmethanethiolStructure of 4-(Trifluoromethyl)phenylmethanethiol[108499-24-7]GEO-02384
2,7,7-Trimethyl-4-(5-((5-methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03524
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